
Dr. Crane was born November 27, 1827, in Huron County, Ohio. (Huron County is now part of Erie County). He is the son of Simeon and Eliza (Ingraham) Crane, natives of Connecticut and Massachusetts, respectively. His father died in 1877, and his mother passed away when C.E. was seven years old. He was reared and educated in Erie County to the age of thirteen, at which time he moved to Norwalk, where he remained until he was twenty-one years old.
He received the main part of his education at the schools of that town, including the study of medicine. In 1848-49 he attended the Western Reserve College where he graduated in 1849. Immediately thereafter, in May of the same year, he moved to Green Bay, then but a small place with bright prospects, and continued in a successful practice until 1892.
In 1861, Dr. Crane was commissioned as assistant surgeon of the Fifth Wisconsin Infantry, joining the regiment in Madison, Wisconsin. In 1863, the doctor was promoted to surgeon. In 1864, he was discharged and returned home to resume practice in Green Bay.
In 1872, Dr. C.E. Crane was married in Green Bay to Mrs. Louise Desnoyers, a native of Pennsylvania and daughter of Captain Beard.

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Besides serving as mayor for five terms, he was President of the School Board for six years and also served on the Board of Health. He was President of the Brown County Medical Society from 1868 to 1880.
Dr. Crane died at age 71, May 8, 1898. The newspaper reported he was the oldest resident physician of the city. He had been sick for several weeks before dying of cancer of the throat.